Canan (BALCI) TARI, PhD Position: Professor E-mail: canantari[at]iyte.edu.tr Telephone: 0090-232-750 6316  Fax: 0090-232-750 6196 Address: Department of Food Engineering, Izmir Institute of Technology, Gulbahce, Urla, Izmir, Turkey Doctor of Philosophy in Chemical Engineering          1993-1998 Illinois Institute of Technology (IIT), Chicago, IL/USA Master of Science in Food Engineering          1991-1994 Ege University, Izmir/Turkey Bachelors of Science in Food Engineering          1986-1991  Ege University, Izmir/Turkey
PROFESSIONAL ACTIVITIES AND EXPERIENCES Izmir Institute of Technology Department of Food Engineering, Izmir, Turkey, Professor, 2003-present) Teaching Fundamentals of Biotechnology, Food and Industrial Microbiology, Advanced Microbiology, Principles of Fermentation Technology. Graduate research;  Scale up and optimization studies on the polygalacturonase production by Aspergillus sojae ; Optimization studies on beta- galactosidase using newly isolated  lactic acid bacteria.  Purification and characterization studies of  polygalacturonase  and beta- galactosidase. Bioethanol production from fungal organisms using renewable resources. Integration of bacterial hemoglobin gene into fungal organism in order to enhance the oxygen uptake rate under oxygen limited fermentation conditions. Conducting molecular biology research as visiting scientist with Illinois Institute of Technology Department of Biology, USA during the summer periods of 2009 to 2011. Illinois Institute of Technology, Department of Biology, IL, USA Adjunct Professor, July 2012- July 2013 (sabbatical). Teaching  Biochemistry Laboratory class at undergraduate level and cooperating research within the department. Scientific Consultant to the Enzyme Company (Mayasan  Inc.  Istanbul,Turkey) 2010-2012.  Research and development, scaling up the production of microbial food enzyme to production scale considering both fermentation and down stream processing Izmir Institute of Technology Department of Food Engineering, Izmir, Turkey Erasmus and ECTS Co-ordinator for the Biotechnology and Bioengineering Programme, 2004-2007 Agean Region Chamber of Industry Co-chair of the University  Part  in the Committee of  University and Industry Relations, 2005-2007 Duties: Bringing university and industry together in common projects, arranging meetings. Guiding students into  industrial projects. International University Bremen Department of Biochemical Engineering , Germany Visiting scientist within the  International Trans Disciplinary Science Programme June –August 2006 Duties: Cooperation on the project titled” Protein electroextraction coupled to direct sorption-a new route for primary  recovery of intracellular bio product from industrial yeast” Valley Research Inc. South Bend IN , USA Process Development Manager, January, 2001-June, 2003 Duties: Responsible for the development and execution of selected projects including developing production and processing technologies. Evaluating and improving existing production processes  used  to ferment, process and formulate enzyme products. Working with outside laboratories and contract manufacturers domestically and international in order to develop and implement new production and process technologies. Assisting quality assurance and technical service in the areas of  microbiology, biochemistry and bioprocessing. Set up in house microbiology and fermentation lab. Supervising lab personnel involved in the in house projects. Reporting to the management with oral and written reports University of Illinois at Chicago , College of Dentistry , Department of Periodontics , USA Research Microbiologist July, 2000-January, 2001 Duties: Growth of aerobic and anaerobic oral bacteria (Streptococcus  species and Porphyromonas gingivalis). Determination of minimum inhibitory antimicrobial agent  concentration  (MIC),  minimum  bactericidal concentration (MBC). Time kill and aggregation tests. Spiral plating of cell cultures for colony count. Being in charge of anaerobic gas chamber.  MycoPharma, Inc. Chicago , USA Research Associate, March – September 1999 Duties:  Fermentation, extraction and purification of immunostimulant glycoproteins from Mycobacteria vaccae.    Ege University Department of Food Engineering, Turkey Research Assistant, 1992-1994 Duties: Teaching dairy technology laboratories; supervising  the dairy pilot plant for pasteurized and  sterilized milk, cheese and yogurt production.                      Pinar Sut , Turkey (Dairy Company) Internship, Summer 1991 Duties: Getting familiar with large-scale production of cheese, butter and yogurt.
Professional Memberships Professional Member of Institute of Food Technologist Member of Society of Industrial Microbiologist  Member of American Society of Microbiology
Peer Reviewer Process Biochemistry Enzyme and Microbial Technology International Journal Food  Science and Technology. Electronic Journal of Biotechnology Journal of Biotechnology Applied Biochemistry and Biotechnology Biochemical Engineering Journal Letters in Applied Microbiology Journal of Scientific and Industrial Research Journal of Chemical Technology and Biotechnology Preparative Biochemistry and Biotechnology
Languages   Turkish (native), English (fluent), German (fluent)
Expert Evaluator Reviewer for EU FP 7-SME 2012 European Union projects  for the benefits for SMEs (2012-2013) EU FP 7-SME 2012 European Union projects  for the benefits for SMEs (2012) EU FP 7-SME 2011 European Union projects  for the benefits for SMEs (2011) EU FP 6 European Union projects, Food Quality and Safety Thematic Priority 5 (2005) TUBİTAK-TEYDEB (Turkish Scientific Research Council -Technology Auditing and Evaluation) 2005 , 2009 TTGV (Turkish Technology and Development Foundation) 2004, 2008   TUBITAK-TOVAG  Project advisor 2009-present
Research Interests Fermentation, Industrial Enzyme Production, Scale up and Optimization, Industrial Biotechnology, Down Stream Processing, Protein Purification, Oral and Food Microbiology , Antibiotic Detection , Starter Cultures, Dairy Technology
Awards  received · Fellowship from DAAD (German Academic Student  Exchange Organization) for practical training in the  University Giessen, Germany, Summer, 1990. · Graduated among the Food Engineering students with second highest GPA (1991). · Fellowship from High Educational Council of Turkey  to conduct Ph.D. in USA (1994 to1998). · Graduated among the Chemical Engineering Ph.D students with academic distinction(1998). · Nominated for the bibliography to be included in Marquis Who is Who in Science and Engineering in Book 8 th Ed. (2005). · Nominated as the international professional of the year, in International Biographical Centre Cambridge, England (2005). · Fellowship from TUBİTAK (Turkish Scientific Research Council) to collaborate in joint research with International University Bremen, Germany (2006). · Fellowship from  International University of Bremen, Germany  within the International Trans Disciplinary Science Program  (2006). · Fellowship from High Educational Council of Turkey  to conduct research as visiting professor  in Illinois Institute of Technology Chicago, IL, USA (2011)
PUBLICATIONS 1. Demir, H., Gogus, N., Tari, C., Heerd, D., Lahore, M.F. (2012) Optimization of the process parameters for the utilization of orange peel to produce polygalacturonase by solid-state fermentation from an Aspergillus sojae mutant strain. Turkish Journal of Biology 36 (doi: 10.3906/biy-1104-23) 2. Heerd, D., Yeğin, S., Lahore, M.F., Tarı, C., (2012) Pectinase production by Aspergillus sojae in solid-state fermentation: A comparative study. Food and  Bioproducts Processing (90) 102-110 3. Büyükkileci,A.O; Tari,C., Lahore , F.M., (2011). Enhanced production of exo-polygalacturonase from agro-based products by Aspergillus sojae. BioResources 6(3) 3452-3468. 4. Yeğin, S., Lahore, M.F., Salgado, A.J.G., Güvenç, U., Göksungur, Y., Tari, C., (2011) Aspartic proteinases from Mucor spp. in cheese manufacturing. Applied Microbiology and Biotechnology  89: 949-960. 5. Tarı, C., Özkan, K., Öncü, Ş., Avcı, T., (2011). The relationship of pellet morphology to polygalacturonase production of Rhizopus oryzae in various media compositions. Gıda 36 (1) 25-31. (English) 6. Ustok, F.I., Tari,C., Harsa,S., (2010) . Biochemical and thermal properties of β-galactosidase enzymes produced by artisanal yoghurt cultures. Food Chemistry 119: 1114-1120. 7. Tarı,C., Ustok, F.I., Harsa,S. (2009). Production of food grade β-galactosidase from artisanal yogurt strains" Food Biotechnology 24: 1-17. 8. Yıldız, O., Unluturk, S., Tarı, C.; (2009). Detection and comparison of different antibiotic residues in UHT cows’ milk using commercial test kits. Academic Food Journal 7(4)19-23. (Turkish) 9. Tokatlı,F.,Tarı,C., Unluturk, M., Baysal,N., (2009) Modeling of polygalacturonase enzyme activity and biomass production by Aspergillus sojae ATCC 20235. accepted for publication in  Journal of Industrial Microbiology & Biotechnology 36(9). 1139-1148. 10. Tari,C., Ustok, F.I., Harsa, S. (2009). Optimization of the associative growth of novel yogurt cultures in the production of biomass, beta galactosidase and lactic acid using response surface methodology. International Dairy Journal. 19:236-243. 11. Vennapusa,R.R. Tari,C. Cabrera, R. Lahore,M.F. (2009) . Surface energetics to asses biomass attachment onto hydrophobic interaction adsorbents in expanded beds. Biochemical Engineering Jounal. 43:16-26. 12. Tari, C., Dogan, N., Gogus, N., (2008) Biochemical and thermal characterization of exo-polygalacturonase produced by Aspergillus sojae. Food Chemistry, 111:824-829 13. Dogan,N., Tarı,C. (2008) Characterization of three phase partitioned exo-polygalacturonase from Aspergillus sojae with unique properties. Biochemical Engineering Journal, 39: 43-50. 14. Unluturk,S.,Atılgan,M., Baysal, A.H., Tari,C., (2008) Use of UV-C radiation as a non-thermal process for liquid egg products (LEP). Journal of Food Engineering. 85: 561-568. 15. Öncü,Ş. Tarı,C., Unluturk,S., (2007) Effect of various process parameters on  morphology, rheology and polygalacturonase production by Aspergillus sojae in a batch bioreactor. Biotechnology Progress, 23: 836-845. 16. Tarı,C., Goguş,N., Tokatlı,F., (2007) Optimization of biomass, Pellet Size and Polygalacturaonase prodcution by  Aspergillus sojae ATCC 20235 Using Response Surface Methodology. Enzyme and Microbial Technology, 40: 1108-1116. 17. Ustok,F.I. Tarı,C. Gogus,N. (2007) Solid state production of polygalacturonase  by Aspergillus sojae ATCC  20235. Journal of Biotechnology, 127: 322-334. 18. Gogüş,N. Tarı,C., Ünlütürk, S., Öncü, Ş., Tokatlı,F. (2006) Effect of various factors on  morphology, rheology and pectinase production by Aspergillus sojae ATCC 20235 and Rhizopus oryzae ATCC 4858 using a statistical approach. Biochemical Engineering Journal, 32: 171-178. 19. Tarı,C. Genckal,H., Tokatlı,F. (2006) Optimization of a growth medium using a statistical approach for  the production of alkaline protease produced from newly isolated Bacillus sp L21.  Process Biochemistry  41: 659-665.   20. Genckal,H. and Tarı,C. (2006) Alkaline Protease Production from Bacillus.sp isolated from natural habitat. Enzyme and Microbial Technology  39: 703-710. 21. Enayati,N., Tarı, C., Parulekar,S. J.; Stark, B.C.; Webster, D.A.; (1999) Production of  a-Amylase in Fed-Batch Cultures of vgb+ and vgb- Recombinant Eschericha coli: Some Observations.  Biotechnology  Progress 15(4), 640-645 (1999). 22. Tarı,C.; Parulekar,S.J.; Stark,B.C.; Webster,D.A.; (1998) Excretion and Synthesis of a- Amylase in vgb+ and vgb  Recombinant  E.coli.,  Bioengineering and Biotechnology  59(6), 673-678.
CONFERENCES 1. Demir, H., Göğüş,N., Tari,C. The Comparison of Biochemical Properties of Exo-Polygalacturonases Produced By Solid State And Submerged Fermentations usıng an Aspergillus sojae mutant strain. International Conference on Enzyme Science and Technology 31 October – 04 November 2011, Kuşadası, TURKEY. (Abstract p123). 2. Gogus, N., Tari, C. Comparison od extracted orange peel and whole orange peel in terms of polygalacturonase production uisng Aspergillus sojae mutant strain. IV International Conference on Environmental, Industrial and Applied Microbiology (BioMicroWorld2011). 14-16 September 2011, Torremolinos,Malaga, Spain. (oral presentation). 3. Demir, H., Tari, C. Bioconversion of wheat bran into polygalacturonase using Aspergillus sojae in solid state fermentation. IV International Conference on Environmental, Industrial and Applied Microbiology (BioMicroWorld2011). 14-16 September 2011, Torremolinos,Malaga, Spain. (oral presentation). 4. Üçüncü,C., Tarı,C., Ozen, B., Demir,H. Optimization of phosphoric acid hydrolysis of fruit pomaces; potential candidates for bioethanol productıon International Food Congress: Novel Approaches in Food Industry, 26-29 May 2011, Altınyunus. Çeşme ,Turkey (poster). 5. Büyükkileci,O., Tarı,C., Lahore, M.F., (2011). Screening of Agricultural Products and Optimization of Medium Composition for Enhanced exo-Polygalacturanase Production by an Aspergillus sojae Mutant. International Food Congress: Novel Approaches in Food Industry, 26-29 May 2011, Altınyunus. Çeşme ,Turkey (poster). 6. Demir, H., Tarı, C., Üçüncü, C., (2011) Production of a pectinase from Aspergillus sojae by solid-state fermentation: Screening of the agro-industrial residues of food industry. International Food Congress: Novel Approaches in Food Industry, 26-29 May 2011, Altınyunus. Çeşme ,Turkey (poster). 7. Hakgüder, B., Unlütürk,S., Gögüş, N., Tarı, C., Lahore,M.F. (2011). Morphology and bulk  rheology affected by operational conditions in submerged fermentation  of Aspergillus sojae. International Food Congress: Novel Approaches in Food Industry, 26-29 May 2011, Altınyunus. Çeşme ,Turkey (poster). 8. Gögüş, N., Hakgüder, B., Tarı,C., Demir, H., Lahore, M.F.(2011). Effect of process parameters on polygalacturonase production by mutant strain of Aspergillus sojae in serial bioreactor system. International Food Congress: Novel Approaches in Food Industry, 26-29 May 2011, Altınyunus. Çeşme ,Turkey (oral presentation). 9. Büyükkileci, A. O.;Tarı, C. Lahore, M.F. (2011) Screening of Agricultural Products and Optimization of Medium Composition for Enhanced exo-Polygalacturanase Production by an Aspergillus sojae Mutant (poster) 10. Heerd, D., Tari, C., Lahore, M. F. (2010) A comporative study on pectinase production by Aspergillus sojae strains in solid-state fermentation Part II. 14th International Biotechnology Symposium and Exhibition 14-18 September 2010, Palacongressi, Rimini, Italy (poster) 11. Buyukkileci, A.O.; Tari, C., Lahore, M.F. (2010) Optimization of exo-polygalacturonase production from orange peel by Aspergillus sojae. 14th International Biotechnology Symposium and Exhibition 14-18 September 2010, Palacongressi, Rimini, Italy (poster) 12. Tarı, C., Gogus, N., Demir, H., Lahore, M.F., Heerd, D.Optimization of Medium Composition for the production of polygalacturonase from a new mutant Aspergillus sojae strain by submerged fermetation.  2nd International Confrence of Food Science and Technology. 22-24 March 2010 Chester, UK. (poster) 13. Heerd, D., Yegin,S., Tarı, C., Lahore, M. F. (2009). A comparative study on pectinase production by Aspergillus sojae strains in solid-state fermentation. Effost Conference , New Challenges in Food Preservation 11-13 November 2009, Budapest, Hungary, P330 (poster) 14. Demir, H., Baysal,N., Tarı,C. Heerd, D., Lahore , M.F.,(2009)  Optimization of Polygalacturonase production from Aspergillus sojae by using orange peel. Effost Conference , New Challenges in Food Preservation 11-13 November 2009, Budapest, Hungary, P331 (poster). 15. Hakguder, B., Ustok, I.F., Tarı,C., Hamamcı, H., Harsa, Ş. Production and characterization of beta –galactosidase by Rhizomucor meihei. Cost 928  2nd Annual Meeting , Istanbul 15-17 October 2008. (oral presentation). 16. Cabuk,B., Harsa,S., Tarı,C., Immobilization of beta-galactosidase onto chitosan-hydroxyapatite composite beads. Cost 928  2nd Annual Meeting , Istanbul 15-17 October 2008. (poster). 17. Dogan,N., Tari, C. (2008) Fed-Batch Production of Polymethylgalacturonase and polygalacturonase by Aspergillus sojae ATCC 20235 usinf face centered central composite design. FoodMicro 2008 Evolving Microbial Food Quality and Safety Aberdeen/Scotland (poster). 18. Ustok, F.I., Hakguden, B., Harsa, S., Tarı,C. 2008. FoodMicro 2008 Evolving Microbial Food Quality and Safety Aberdeen/Scotland (poster). 19. Vennapusa,R., Tari,C. Cabrera, R.B., Lahore, Fernandez-M., (2008) Surface energetics to assess biomass attachment onto hydrophobic interaction adsorbents in expanded beds, 28th International Symposium on the Separation of Proteins, Peptides and Polynucleotides,Baden/Germany. (oral presentation)  20. Ustok,F.I., Tari,C., Harsa,Ş. (2007) Biochemical properties of beta-galactosidase produced by novel yoghurt culture.  2nd International Cogress on Food and Nutrition. Istanbul, Turkey (Poster).  21. Yıldız,O., Unluturk,S., Tarı,C., (2007) An evaluation and comparison of different rapid tests and electrical conductivity for detection of ampicillin in cows milk. 2nd International Cogress on Food and Nutrition. Istanbul, Turkey (poster). 22. Dogan,N., Tari,C., Gogus, N. (2007) Kinetic and Thermodynamic Properties of Crude and Three-Phase Partitioned Polygalacturonase from Aspergillus sojae. 13th European Congress on Biotechnology. Barcelona , Spain . Abstract in Journal of Biotechnology 131:2S, p:224:28. 23. Ustok,F.I., Tari,C., Harsa, Ş. (2007) Effect of symbiotic relationship of Lactobacillus bulgaricus 77 and Streptococcus thermophilus 95/2 on beta-galactosidase and lactic acid production. 13th European Congress on Biotechnology. Barcelona , Spain . Abstract in Journal of Biotechnology 131:2S, p: 224:29. 24. Yıldız,O., Unluturk,S., Unluturk,M., Tarı,C., (2007) Electrical conductivity can be used as a rapid tool for detection of antibiotics in cow’s milk? (2007). 5th International Congress on Food Technology, Thesssaloniki  ( Greece ). v:1. p:71-77. 25. Dogan,N., Tarı,C., (2007) Characterization of three phased partitioned polygalacturonase produced by Aspergillus sojae ATCC 20235. 5th International Congress on Food Technology, Thesssaloniki  ( Greece ). v:1. p:307-313. 26. Tarı, C.,Ozkan,K., Sofuoglu,A., (2007) Effects of various media parameters on the pellet morphology, polygalacturonase and ethanol production of Rhizopus oryaze. 5th International Congress on Food Technology, Thesssaloniki  ( Greece ). v:1. p:299-307. 27. Gogus,N., Tarı,C., Dogan,N. (2007) Biochemical properties of Aspergillus sojae ATCC 20235 polygalacturonase. 5th International Congress on Food Technology, Thesssaloniki  ( Greece ). v:1.p:271-276. 28. Ustok,F.I. Tarı, C., Harsa,S.(2007) Screening of Streptococcus thermophilus ssp. Isolated from traditional Turkish yogurts for β -galactosidase and lactic acid production. 5th International Congress on Food Technology, Thesssaloniki  ( Greece ). v:1. p:277-284. 29. Oncu,S., Unluturk, S., Tarı, C. (2007) “The role of aeration ın pectinase fermentation of Aspergillus sojae. 5th International Congress on Food Technology, Thesssaloniki  ( Greece ). v:1. p:258-265. 30. Atılgan, M., Unluturk,S., Baysal,A.H., Tarı,C., (2007) Short wave ultra violet (UVC) inactivation of Escheriae coli (ATCC 8739) in liquid egg white. 5th International Congress on Food Technology, Thesssaloniki  ( Greece ). v:2. p:358-365. 31. Tarı,C., Gögus,N., Oncü,S., Unluturk,S.,Tokatli,F (2006) Investigating the effect of various on morphology , rheology and production  of pectinase by using a statistical approach. 3rd Central European Congress on Food ,  Sofia ( Bulgaria ).  p: 101. 32. Ustok,F.I., Tarı,C., Gogus,N., (2006). Solid state production of Polygalacturonase by Aspergillus sojae ATCC 20235. 3rd Central European Congress on Food , Sofia ( Bulgaria ).  p: 106. 33. Tarı,C. Genckal,H., Tokatli,F., (2006) Growth medium optimization for the production of alkaline protease from a newly ısolated Bacillus sp.L21 3 rd Central European Congress on Food, Sofia ( Bulgaria ).  p: 156. 34. Oncu,S., Unluturk,S., Tarı,C. , Goguş,N., (2006) Investigation of various factors affecting the pellet morphology , broth rheology  and pectinase  production in submerged fermentation of Aspergillus sojae.  3 rd Central European Congress on Food, Sofia ( Bulgaria ).  p: 221.  35. Gogüş,N. Tarı, C., Ünlütürk, S., Öncü, Ş., Tokatlı,F.,(2006) Optimization of various fermentation parameters using Aspergillus sojae ATCC 20235 as a new pectinase producer. FoodMicro2006, The 20th International ICFMH Symposium, Bologna, Italy. p.272 36. Öncü,Ş., Ünlütürk,S., Tarı,C., Goguş,N., (2006) Effect of agitation speed on the pellet morphology, broth rheology and pectinase enzyme production in submerged fermentation. FoodMicro2006, The 20th International ICFMH Symposium,Bologna, Italy.p.279 37. Gogüş,N. Tarı, C., Ünlütürk,S., Öncü,Ş., Tokatlı,F. (2006) Optimization of the morphology and pectinase production by Aspergillus sojae ATCC 20235 using response surface methodology. Proceedings of IUFoST 13th World Congress of Food Science and Technology Nantes, France p. 332. 38. Öncü, Ş., Ünlütürk,S., Tarı,C., Goguş,N., (2006) Investigation of various factors affecting the pellet  morphology, broth rheology and pectinase enzyme production in submerged fermentation of Aspergillus sojae. Proceedings of IUFoST, 13th World Congress of Food Science and Technology, Nantes, France, p1253-1264, DIO: 10.1051/IUFoST 20060271. 39. Enayati, N., Tarı,C., Parulekar, S.J.;(1999) Production of a-Amylase and ß-Lactamase  in Fed-Batch Cultures of vgb+ and vgb- Recombinant Eschericha coli. Proceedings of the Annual  AICHE Meeting, Dallas-USA. Paper 60f. 40. Tarı, C.; Parulekar,S.J.; Stark,B.C.; Webster,D.A.; (1996) Excretion and Synthesis of a- Amylase in vgb+ and vgb  Recombinant E.coli., Annual AICHE
PROJECTS Bioprocess platform for the A.sojae PGzyme system  (PGSYS EXCHANGE FP-7 IRSES 269211, principle investigator of Turkey part. The impact of bioprocessing strategy on the production and downstreaming of polygalacturonase by Aspergillus sojae.(Eurotrans-Bio ETB-2008-44, principal investigator  of Turkey part) Production and downstream processing of the polygalacturonase from Aspergillus sojae: The effect of micobial morphology and fluid rheology on system global productivity under conditions close to industrial prcatice. A theoretical and experimental approach. (TUBITAK–Germany BMBF-IntentC-107O602, 2008, principal investigator  of Turkey part) Investigation of the factors influencing the morphology of Rhizopus oryzae in submerged fermentation (principal investigator IYTE 2006-37) Development of a rapid antibiotic detection kits (biosensor) for milk and milk products (principal investigator IYTE 2005 -37). Effect of the morphology of Aspergillus sojae on pectinase enzyme production and optimization of the fermentation conditions (principal investigator IYTE 2004-04). Optimization of the production of the lactase enzyme from newly isolated yogurt and cheese cultures ( co-researcher TUBİTAK AB COST-TOVAK-1040270) UV Disinfection of liquid egg products (co-researcher, TUBITAK-104O210- 2005).
COURSES · FE 503 Advanced Microbiology · FE 524 Principles of Different Fermentation Methods · BTEC 507 Fundamentals of Biotechnology I · FE 518  Food and Industrial Microbiology · FE 527 Enzyme Engineering · FE 514  Food Biotechnology · FE 805 Special Studies · FE 905 Special Studies